Identifying Functional Elements by Comparative DNA Sequence Analysis
نویسندگان
چکیده
منابع مشابه
Identifying functional elements by comparative DNA sequence analysis.
Functional elements in DNA sequences tend to evolve at a much slower rate than nonfunctional sequences, because functional elements are subject to selective pressure. Comparative DNA sequence analysis exploits this local difference in mutation rates to identify functional elements such as genes, regulatory sequences, splice sites, and binding sites. This is accomplished by comparing orthologous...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2001
ISSN: 1088-9051
DOI: 10.1101/gr.197101